Neuroprotective effects of a specific multi-nutrient intervention against Aβ42-induced toxicity in rats.
Loss of brain cells in Alzheimer’s disease is believed to be caused by toxic amyloid peptides. This proces is thought to start at the neuronal membrane, where the composition of the membrane may influence the toxicity level. We now tested whether a dietary intervention with specifically those nutrients that are involved in membrane synthesis, either as a precursor or as a cofactor, would affect amyloid-induced toxicity. In rats on a normal control diet, amyloid infusion caused neuronal cell loss and induced behavioural changes. These effects were not observed in rats on the special Fortasyn Connect diet. The present study shows that Fortasyn Connect has a protective effect against amyloid toxicity.